Abl 1b isoform E528K SH3-SH2-KD (aa 83-534) in complex with imatinib

ABL1 regulatory core SH3-SH2-Kinase domain (83-534) with point mutation E528K in complex with imatinib
E528K SH3SH2KD(83-534) in complex with imatinib

Abl kinase domain in complex with PD173955

Abl kinase domain in complex with imatinib

Abl E528K SH3SH2KD in complex with imatinib

The molecular basis of Abelson kinase regulation by its aI-helix

Abelson tyrosine kinase, cancer, chronic myelogenous leukemia, allosteric activation, aI-helix, asciminib, NMR

ABL1 E528K SH3-SH2-Kinase Domain (residues 83-534, isoform 1b)
point mutation E528K; first two amino acids (GP) from cleavage site

co-expression with phosphatase PTP1 plus a separate plasmid that expresses lamda phosphatase (LPP)

subdirectory nmr_p has NMRPipe processing file and subdirectory add_files contains all Bruker list files and the pulse program, experiments 233, 232, 231 were recorded identically and need to be added.

Abl 1b isoform wild type SH3-SH2-KD (aa 83-534) apo

Abl 1b isoform wild type SH3-SH2-KD (aa 83-534) in complex with asciminib

Abl 1b isoform wild type SH3-SH2-KD (aa 83-519) apo

Abl 1b isoform wild type SH3-SH2-KD (aa 83-519) in complex with imatinib

Abl 1b isoform wild type SH3-SH2-KD (aa 83-517) apo

Abl 1b isoform wild type SH3-SH2-KD (aa 83-517) in complex with imatinib

Abl 1b isoform wild type SH3-SH2-KD (aa 83-515) apo

Abl 1b isoform wild type SH3-SH2-KD (aa 83-515) in complex with imatinib

Abl 1b isoform E528K SH3-SH2-KD (aa 83-534) apo

Abl 1b isoform wild type SH3-SH2-KD (aa 83-534) in complex with GNF-5

Abl 1b isoform wild type SH3-SH2-KD (aa 83-534) in complex with PD166326

Abl 1b isoform wild type SH3-SH2-KD (aa 83-534) in complex with imatinib