Crystal structure of VIM-2 with hydrolyzed faropenem (ring-open form)

(5~{Z})-2-[1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-5-(4-oxidanylbutylidene)-2~{H}-1,3-thiazole-4-carboxylic acid

Faropenem reacts with serine and metallo-beta-lactamases to give multiple products.

Class B beta-lactamase,Class B carbapenemase VIM-2,Metallo beta lactamase VIM-2,Metallo beta-lactamase,Metallo-beta-lactamase VIM-2,Metallo-beta-lactamase vim-2,Mettalo-beta-lactamase VIM-2,VIM-2 metallo-beta-lactamase,VIM-2 protein

blaVIM-2, bla vim-2, bla-VIM-2, blasVIM-2, blaVIM2, blm, VIM-2, vim-2, PAERUG_P32_London_17_VIM_2_10_11_06255

National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)

metallo-beta-lactamase, antibiotic, faropenem, catalysis, ANTIMICROBIAL PROTEIN