Human UDP-Glucose Dehydrogenase A225L substitutuion with UDP-xylose bound

The A225L Substitution of hUGDH alters structure and function

10% PEG3350, 16% 1,5-pentanediol, 100 mM HEPES

National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)

Assembly supported by sedimentation velocity experiments using analytical ultracentrifugation.

UDP-glucose 6-dehydrogenase (E.C.1.1.1.22)
dehydrogenase, udp-xylose, hUGDH, OXIDOREDUCTASE