Structure of the ARTT motif Q212A mutant C3bot1 Exoenzyme (NAD-bound state, crystal form I)

Structural Basis for the Nad-Hydrolysis Mechanism and the Artt-Loop Plasticity of C3 Exoenzymes.

Nad Binding Induces Conformational Changes in Rho Adp-Ribosylating Clostridium Botulinum C3 Exoenzyme.

22.5% PEG 3350 W/W, 100 MM LI2SO4, 100 MM SODIUM CITRATE PH 3.0, 3-10% MPEG 550 V/V

THE CRYSTAL STRUCTURE OF EXOENZYME C3 FROM CLOSTRIDIUM BOTULINUM

STRUCTURE OF THE CLOSTRIDIUM BOTULINUM C3 EXOENZYME (L177C MUTANT)

STRUCTURE OF THE CLOSTRIDIUM BOTULINUM C3 EXOENZYME (WILD-TYPE) IN COMPLEX WITH NAD

C3 EXOENZYME FROM CLOSTRIDIUM BOTULINUM, TETRAGONAL FORM

CRYSTAL STRUCTURE OF THE C3BOT-RALA COMPLEX REVEALS A NOVELTYPE OF ACTION OF A BACTERIAL EXOENZYME

CRYSTAL STRUCTURE OF THE C3BOT-NAD-RALA COMPLEX REVEALS ANOVEL TYPE OF ACTION OF A BACTERIAL EXOENZYME

MOLECULAR RECOGNITION OF AN ADP-RIBOSYLATING CLOSTRIDIUM BOTULINUM C3 EXOENZYME BY RALA GTPASE

STRUCTURE OF THE WILD-TYPE C3BOT1 EXOENZYME (FREE STATE, CRYSTAL FORM I)

STRUCTURE OF THE WILD-TYPE C3BOT1 EXOENZYME (NICOTINAMIDE-BOUND STATE, CRYSTAL FORM I)

STRUCTURE OF THE ARTT MOTIF Q212A MUTANT C3BOT1 EXOENZYME (FREE STATE, CRYSTAL FORM II)

STRUCTURE OF THE ARTT MOTIF Q212A MUTANT C3BOT1 EXOENZYME (FREE STATE, CRYSTAL FORM I)

STRUCTURE OF THE ARTT MOTIF E214N MUTANT C3BOT1 EXOENZYME (FREE STATE, CRYSTAL FORM III)

STRUCTURE OF THE ARTT MOTIF E214N MUTANT C3BOT1 EXOENZYME (NAD-BOUND STATE, CRYSTAL FORM III)

STRUCTURE OF THE PN LOOP Q182A MUTANT C3BOT1 EXOENZYME (FREE STATE, CRYSTAL FORM I)

STRUCTURE OF THE PN LOOP Q182A MUTANT C3BOT1 EXOENZYME (NAD-BOUND STATE, CRYSTAL FORM I)

ADP-RIBOSYLATES EUKARYOTIC RHO AND RAC PROTEINS ON AN
ASPARAGINE RESIDUE
ENGINEERED RESIDUE IN CHAIN A, GLN 212 TO ALA
ENGINEERED RESIDUE IN CHAIN B, GLN 212 TO ALA
ENGINEERED RESIDUE IN CHAIN C, GLN 212 TO ALA
ENGINEERED RESIDUE IN CHAIN D, GLN 212 TO ALA

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS.

MONO-ADP-RIBOSYLTRANSFERASE C3 (E.C.2.4.2.-)

C3 EXOENZYME, ARTT MOTIF, BACTERIAL TOXINS, GLYCOSYLTRANSFERASE, TRANSFERASE