Crystal structure of murine polyomavirus RA strain VP1 in complex with the GT1a glycan

Structural and Functional Analysis of Murine Polyomavirus Capsid Proteins Establish the Determinants of Ligand Recognition and Pathogenicity.

N- and C-terminally truncated version of VP1. The first 4 amino acids at the N-terminus belong to the purification tag.

N-acetyl-alpha-neuraminic acid-(2-8)-N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-beta-D-galactopyranose

Murine polyomavirus (strain P16 small-plaque)

1.7 M ammonium sulfate
4.9% (v/v) isopropanol

1VPS contains the same protein complexed with a different glycan.

1VPN contains the same protein without any complexed glycans.

U VALUES : WITH TLS ADDED HYDROGENS HAVE BEEN USED IF PRESENT IN THE INPUT

Major Capsid Protein of Murine polyomavirus RA Strain

Murine Polyomavirus, Virus protein, carbohydrate complex, virus-host interaction, viral protein