Crystal structure of human Fab CAP256-VRC26.25, a potent V1V2-directed HIV-1 broadly neutralizing antibody

New Member of the V1V2-Directed CAP256-VRC26 Lineage That Shows Increased Breadth and Exceptional Potency.

Fab Heavy chain of broadly neutralizing antibody VRC26.25

Fab Light chain of broadly neutralizing antibody VRC26.25

Crystals grown in a reservoir solution of 23% PEG 8000 and 0.1M HEPES pH 7.5 and flash frozen in liquid nitrogen with 20% PEG 400 as a cryoprotectant

Fab Heavy chain of broadly neutralizing antibody VRC26.25, Fab Light chain of VRC26.25

VRC26, CAP256, V1V2, HIV-1, Env, Envelope, Broadly Neutralizing, superinfection, IMMUNE SYSTEM