Structure of HOXB13 complex with methylated DNA

Impact of cytosine methylation on DNA binding specificities of human transcription factors.

DNA (5'-D(P*TP*TP*GP*TP*GP*TP*TP*TP*TP*AP*(5CM)P*GP*AP*GP*GP*TP*CP*C)-3')

DNA (5'-D(P*GP*GP*AP*CP*CP*TP*(5CM)P*GP*TP*AP*AP*AP*AP*CP*AP*CP*AP*A)-3')

PEG 3350, potassium chloride, magnesium chloride, 2-methyl-1-propanol, Tris

transcription factor, methylated DNA, complex, transcription