Crystal Structure of Desulfo-Xanthine Oxidase with Xanthine

PHOSPHONIC ACIDMONO-(2-AMINO-5,6-DIMERCAPTO-4-OXO-3,7,8A,9,10,10A-HEXAHYDRO-4H-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-7-YLMETHYL)ESTER

Substrate Orientation and Catalysis at the Molybdenum Site in Xanthine Oxidase: CRYSTAL STRUCTURES IN COMPLEX WITH XANTHINE AND LUMAZINE.

2Fe-2S ferredoxin-type domain, residues 1-165

AD-binding PCMH-type domain, residues 224-528

PEG 8000, pH 7.2, batch, temperature 298K

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS, MOM IS IN THE DESULFO FORM WITH AN ADDITIONAL OXYGEN IN PLACE OF THE SULFUR IN THE COORDINATION SPHERE
enzyme catalysis, desulfo, substrate orientation, xanthine, FAD, Flavoprotein, Iron, Iron-sulfur, Metal-binding, Molybdenum, NAD, Oxidoreductase, Peroxisome