Crystal structure of the calponin homology domain of IQGAP1

The IQGAP1 N-terminus Forms Dimers and the Dimer Interface is Required for Binding F-actin and Ca2+/calmodulin.

Ras GTPase-activating-like protein IQGAP1
N terminal calponin homology domain (UNP residues 1-191)

0.2M-0.3M Ammonium acetate, 20 % PEG 3350, 0.1M Tris, pH 8.5, VAPOR DIFFUSION, SITTING DROP, temperature 277K

all Helical, Calmodulin-binding, Cell membrane, Membrane, Phosphoprotein, PROTEIN BINDING, MEMBRANE PROTEIN