Human DNA polymerase eta R61A-DNA ternary complex: reaction with 1 mM Mg2+ for 40s

Capture of a third Mg2+ is essential for catalyzing DNA synthesis.

DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3')

RAD30 homolog A,Xeroderma pigmentosum variant type protein

National Institutes of Health/National Institute of Diabetes and Digestive and Kidney Disease (NIH/NIDDK)

in crystallo reaction, DNA polymerase, metal ion dependent catalysis, REPLICATION, TRANSFERASE-DNA complex