Crystal structure of bH1 Fab variant (CDR H3 loop design 13_0346) in complex with VEGF

Crystal structure of bH1 Fab CDR H3 loop variants in apo form and in complex with VEGF

ADAPTing Antibody H3 Loops to Cognate Antigens Using Human Germline Derived Sequences

CDR H3 loop design 13_0346 (ARGGSFYYYYMDV)

Isoform L-VEGF206 of Vascular endothelial growth factor A

0.2 M Sodium acetate, 0.1 M HEPES pH 7.5, 20 %(w/v) PEG 3000

Natural Sciences and Engineering Research Council (NSERC, Canada)

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS U VALUES : REFINED INDIVIDUALLY

Fab-antigen complex, CDR H3 loop, VEGF, antibody design, IMMUNE SYSTEM