Structure of the catalytic domain of PARP1

Dissecting the molecular determinants of clinical PARP1 inhibitor selectivity for tankyrase1.

PARP-1,ADP-ribosyltransferase diphtheria toxin-like 1,ARTD1,DNA ADP-ribosyltransferase PARP1,NAD(+) ADP-ribosyltransferase 1,ADPRT 1,Poly[ADP-ribose] synthase 1,Protein poly-ADP-ribosyltransferase PARP1

Buffer: 0.1 M bicine (pH 9.00)
Precipitant: 2.4 M Ammonium sulfate

Poly [ADP-ribose] polymerase 1 (E.C.2.4.2.30,2.4.2.-)