Crystal structure of the dengue 2 virus envelope protein in complex with n-octyl-beta-D-glucoside

A Ligand-Binding Pocket in the Dengue Virus Envelope Glycoprotein.

The Envelope Glycoprotein from Tick-Borne Encephalitis Virus at 2 A Resolution.

DENGUE VIRUS TYPE 2 MAJOR ENVELOPE PROTEIN E

11% PEG 8K, 1M NACL, 0.1M TRIS/HCL PH 9.0, 20% GLYCEROL,0.5% OCTYLGLUCOSIDE

CRYSTAL STRUCTURE OF THE DENGUE 2 VIRUS ENVELOPE PROTEIN IN COMPLEX WITH N-OCTYL- BETA-D-GLUCOSIDE

CRYSTAL STRUCTURE OF THE DENGUE 2 VIRUS ENVELOPE PROTEIN

CRYSTAL STRUCTURE OF THE DENGUE 2 VIRUS ENVELOPE GLYCOPROTEIN IN THE POSTFUSION CONFORMATION

HELIX
DETERMINATION METHOD: AUTHOR PROVIDED.

SHEET
DETERMINATION METHOD: AUTHOR PROVIDED.

RESIDUES 100-108 FORM THE GLYCINE-RICH, HYDROPHOBIC FUSION PEPTIDE (ALLISON ET AL., J.VIROL. 75, 4268-75 (2001))

RESIDUES 270-279 FORM THE KL-HAIRPIN, WHICH MEDIATES THE FUSION-ACTIVATING CONFORMATIONAL CHANGE. THE KL HAIRPIN IS IN THE OPEN CONFORMATION.

NCS GROUP1, RESIDUES 52-131 AND AND 193-279; NCS GROUP 2, RESIDUES 1-51, 132-192, 280-295; NCS GROUP 3, RESIDUES 296-394

VIRAL PROTEIN, MEMBRANE FUSION, FLAVIVIRUS, FUSION PEPTIDE, LOW-PH CONFORMATIONAL CHANGE, CLASS 2 FUSION PROTEIN