Crystal structure of 2-amino-2-desoxyisochorismate synthase (ADIC) synthase PhzE from Burkholderia lata 383 in complex with benzoate, pyruvate and glutamine

2-AMINO-4-(AMINO-3-OXO-PROPYLSULFANYLCARBONYL)-BUTYRIC ACID

Ligand Binding Induces an Ammonia Channel in 2-Amino-2-desoxyisochorismate (ADIC) Synthase PhzE.

Anthranilate/para-aminobenzoate synthases component I

0.1 M HEPES, 0.2 M Mg-chloride, 22% isopropanol, pre-incubation on ice for 30' with 50 mM Mg-chloride, 20 mM glutamine, 20 mM chorismate, streak-seeding, pH 7.1, vapor diffusion, hanging drop, temperature 276K, VAPOR DIFFUSION, HANGING DROP

HYDROGENS HAVE BEEN USED IF PRESENT IN THE INPUT

Anthranilate/para-aminobenzoate synthases component I (E.C.4.1.3.27)

ammonia channel, chorismate, type 1 glutamine amidotransferase, phenazine biosynthesis, LYASE, synthase, BIOSYNTHETIC PROTEIN