Yeast CTP Synthase (Ura7) Bundle bound to Products at low pH

Cryo-EM structures of CTP synthase filaments reveal mechanism of pH-sensitive assembly during budding yeast starvation.

Residues ILE 273 and THR 276, that are next to each other in the sample sequence in every chain, are not properly linked: distance between C and N is 6.19 A.

Residues GLU 299 and GLU 302, that are next to each other in the sample sequence in every chain, are not properly linked: distance between C and N is 6.39 A.

Residues MET 443 and MET 455, that are next to each other in the sample sequence in every chain, are not properly linked: distance between C and N is 5.62 A.

CTP Synthase Bundle assembled with Products

PACBIOSEQ_LOCUS169, PACBIOSEQ_LOCUS176, PACBIOSEQ_LOCUS177, PACBIOSEQ_LOCUS179

National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)