SOLUTION NMR STRUCTURE OF THE HUMAN ETS1/DNA COMPLEX, 25 STRUCTURES

Correction of the NMR structure of the ETS1/DNA complex.

DNA (5'-D(*TP*CP*GP*AP*GP*CP*CP*GP*GP*AP*AP*GP*TP*TP*CP*GP*A)-3')

DNA (5'-D(*TP*CP*GP*AP*AP*CP*TP*TP*CP*CP*GP*GP*CP*TP*CP*GP*A)-3')

THE RESTRAINED REGULARIZED MEAN STRUCTURE IS PRESENTED IN ENTRY 2STW AND 25 STRUCTURES ARE PRESENTED IN ENTRY 2STT. IN 2STW THE LAST COLUMN REPRESENTS THE RMS OF THE 25 INDIVIDUAL SIMULATED ANNEALING STRUCTURES ABOUT THE MEAN COORDINATE POSITIONS. THE LAST COLUMN IN THE INDIVIDUAL SA STRUCTURES HAS NO MEANING. BEST FITTING TO GENERATE THE AVERAGE STRUCTURE IS WITH RESPECT TO RESIDUES 24 - 105 OF THE PROTEIN AND BASE PAIRS 1 - 17 OF THE DNA (RESIDUES 10 - 24 ARE DISORDERED IN SOLUTION). RESIDUE 10 CORRESPONDS TO RESIDUE 320 OF THE NATURAL SEQUENCE. NOTE THE OCCUPANCY FIELD HAS NO MEANING.

DEOXYRIBONUCLEIC ACID, COMPLEX (DNA-BINDING PROTEIN-DNA), DNA BINDING PROTEIN-DNA COMPLEX