Crystal structure of SARS-CoV-2 main protease in complex with an inhibitor TKB-272

Inhibitor TKB-272, hemithioacetal bound form

TKB272, an Orally Available SARS-CoV-2-Mpro Inhibitor Containing 5-Fluorobenzothiazole, Potently Blocks SARS-CoV-2 Replication without Ritonavir

3CL-PRO,3CLp,Main protease,Mpro,Non-structural protein 5,nsp5,SARS coronavirus main proteinase

Severe acute respiratory syndrome coronavirus 2

National Institutes of Health/National Cancer Institute (NIH/NCI)

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS

SARS-CoV-2 main protease, 3C-like proteinase, VIRAL PROTEIN, SARS-CoV-2