Crystal structure of mouse TLR4/MD-2/LPS complex

(R)-((2R,3S,4R,5R,6R)-3-HYDROXY-2-(HYDROXYMETHYL)-5-((R)-3-HYDROXYTETRADECANAMIDO)-6-(PHOSPHONOOXY)TETRAHYDRO-2H-PYRAN-4-YL) 3-HYDROXYTETRADECANOATE

Structural basis of species-specific endotoxin sensing by innate immune receptor TLR4/MD-2

18% PEG3350, 0.2M sodium tartrate, 0.1M Bis-Tris propane, pH 7.5, VAPOR DIFFUSION, SITTING DROP, temperature 293K

HYDROGENS HAVE BEEN USED IF PRESENT IN THE INPUT

Toll-like receptor 4, Lymphocyte antigen 96

Leucine rich repeat MD-2 related lipid recognition, receptor innate immunity, lipid binding, glycosylation, secreted, IMMUNE SYSTEM