Crystal structure of LSD1 in complex with compound S1427

2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.

1-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.

Design and Synthesis of Tranylcypromine-Derived LSD1 Inhibitors with Improved hERG and Microsomal Stability Profiles.

BRAF35-HDAC complex protein BHC110,Flavin-containing amine oxidase domain-containing protein 2

Japan Society for the Promotion of Science (JSPS)

chain 'A' and (resid 172 through 371 )

chain 'A' and (resid 372 through 579 )

chain 'A' and (resid 580 through 832 )

DEMETHYLASE, AMINE OXIDASE, CHROMATIN, HISTONE, FAD, MECHANISM-BASED INHIBITOR, OXIDOREDUCTASE