CDK2-CyclinE1 in complex with allosteric inhibitor I-125A.

2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.

Expanding the ligandable proteome by paralog-hopping with covalent probes

Cell division protein kinase 2,p33 protein kinase

0.21 M sodium citrate tribasic dihydrate, 19.5% PEG3350

National Institutes of Health/National Cancer Institute (NIH/NCI)

kinase, CELL CYCLE-TRANSFERASE-INHIBITOR complex