CryoEM structure of human presequence protease in partial open state 2

Structural basis for the mechanisms of human presequence protease conformational switch and substrate recognition.

20 mM Tris, pH 7.7, 150 mM NaCl, 10mM KCl, 20 mM EDTA and 1 mM 2-mercaptoethanol

CryoEM map of Human Presequence Protease in partial open state 1

Escherichia coli 'BL21-Gold(DE3)pLysS AG'

hPreP,Pitrilysin metalloproteinase 1,hMP1

National Institutes of Health/National Institute on Aging (NIH/NIA)